SCHEMBL1781223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1783736	0.93	TRPV1 (0.44)	RAB9AMAPTNPC1SMN1; SMN2TP53
	SCHEMBL987860	0.91	TRPV1 (0.45)	RAB9AMAPTNPC1TP53MEN1
	SCHEMBL3826237	0.90	CYP3A4 (0.53)	RAB9AMAPTNPC1SMN1; SMN2ALDH1A1
	SCHEMBL10819912	0.90	TRPV1 (0.43)	RAB9AMAPTNPC1SMN1; SMN2TP53
	SCHEMBL3823843	0.90	NPC1 (0.47)	RAB9AMAPTNPC1TP53ALDH1A1
	SCHEMBL987530	0.90	TRPV1 (0.43)	RAB9AMAPTNPC1SMN1; SMN2TP53
	Hydrochloric Acid SCHEMBL3559784	0.90	TRPV1 (0.44)	RAB9AMAPTNPC1TP53MEN1
	Hydrochloric Acid SCHEMBL4999130	0.89	NPC1 (0.46)	RAB9AMAPTNPC1TP53ALDH1A1
	Hydrochloric Acid SCHEMBL3827933	0.89	TRPV1 (0.42)	RAB9AMAPTNPC1SMN1; SMN2TP53
	SCHEMBL3950608	0.89	SCD (0.52)	MAPTTP53ALDH1A1KMT2ATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.