Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.55 |
| ▸ | KDM5A | P29375 | 6/20 | 0.55 |
| ▸ | KDM5C | P41229 | 5/20 | 0.55 |
| ▸ | KDM6B | O15054 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | KDM4A | O75164 | 3/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.55 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17555380 | 0.86 | CYP1A2 (0.62) | CYP1A2POLBKDM5BKDM4CKDM5A | |
| SCHEMBL16055756 | 0.85 | KDM4E (0.65) | CYP1A2POLBKDM5BKDM4CKDM5A | |
| SCHEMBL18415056 | 0.85 | CYP1A2 (0.61) | CYP1A2POLBKDM5BKDM4CKDM5A | |
| 2-Ethylisonicotinamide SCHEMBL2606610 | 0.83 | CYP1A2 (0.69) | CYP1A2POLBKDM5BKDM4CKDM5A | |
| SCHEMBL2305108 | 0.82 | KDM4C (0.57) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL7670706 | 0.82 | KDM4C (0.57) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL16055788 | 0.82 | KDM5B (0.63) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL28162381 | 0.81 | KDM4C (0.52) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL28092824 | 0.81 | KDM5A (0.58) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL31191238 | 0.81 | KDM4C (0.55) | KDM5BKDM4CKDM5AKDM5CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116944505-A | MOF structure-based composite wave-absorbing material and preparation method and application thereof | 中国科学院赣江创新研究院 | 2023-10-27 | — | — | CN | claimed |
| CN-116944494-A | MOF-derived multi-element rare earth-based composite wave-absorbing material and preparation method thereof | 中国科学院赣江创新研究院 | 2023-10-27 | — | — | CN | claimed |
| EP-1453837-A4 | TARGETED THERAPEUTICS AND USES THEREOF | ACTIVBIOTICS INC (US) | 2007-11-07 | — | — | EP | claimed |
| US-7122525-B2 | Targeted therapeutics and uses thereof | ACTIVBIOTICS, INC. (US) | 2006-10-17 | — | — | US | claimed |
| EP-1453837-A2 | TARGETED THERAPEUTICS AND USES THEREOF | Activbiotics, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040063718-A1 | Targeted therapeutics and uses thereof | ACTIVBIOTICS PHARMA LLC | 2004-04-01 | — | — | US | claimed |
| WO-2003045319-A2 | TARGETED THERAPEUTICS AND USES THEREOF | ACTIVBIOTICS, INC. (US) | 2003-06-05 | — | — | WO | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |
| US-20240327382-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 | ALMAC DISCOVERY LIMITED (GB) | 2024-10-03 | — | — | US | disclosed |
| CN-118005944-A | Antibacterial metal organic framework composite material and preparation method and application thereof | 中国科学院赣江创新研究院 | 2024-05-10 | — | — | CN | disclosed |
| EP-4313295-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | Almac Discovery Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| CN-117447962-A | Rare earth-based organic framework composite material and preparation method and application thereof | 中国科学院赣江创新研究院 | 2024-01-26 | — | — | CN | disclosed |
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-4111946-A | Preparation of 3-(pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4075217-A | Conversion of 3-(pyridinyl)-2-cyclohexen-1-one to 3-(pyridinyl)anilines | STERLING DRUG INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4046768-A | 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-4045446-A | 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4033753-A | HERICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4026900-A | 3-(Pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327382-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 | USP19, USP18, UBE2I | CYP1A2 863/4885POLB 2444/4885KDM5B 451/4885 |
| US-20040063718-A1 | Targeted therapeutics and uses thereof | CD47, RIF1, NUP205 | CYP1A2 3572/4885POLB 3642/4885KDM5B 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.