Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.57 |
| ▸ | KDM5C | P41229 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | KDM4A | O75164 | 5/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.57 |
| ▸ | KDM6B | O15054 | 4/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.57 |
| ▸ | KDM5A | P29375 | 3/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.57 |
| ▸ | TET3 | O43151 | 1/20 | 0.57 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ASPH | Q12797 | 1/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.57 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.57 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305108 | 0.84 | KDM4C (0.57) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL845767 | 0.82 | KDM4C (0.55) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL12252467 | 0.82 | GABRP (0.58) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL7668183 | 0.82 | CYP1A2 (0.47) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL31191238 | 0.82 | KDM4C (0.55) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL30560163 | 0.82 | KDM4C (0.55) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL1647272 | 0.82 | CYP1A2 (0.61) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL28331934 | 0.82 | KDM4C (0.55) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| Hydrochloric Acid SCHEMBL1244313 | 0.81 | GABRP (0.56) | KDM4CKDM5CKDM4EKDM4AKDM5B | |
| SCHEMBL481039 | 0.79 | KDM4C (0.52) | KDM4CKDM5CKDM4EKDM4AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |