Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126898 | 0.85 | TRPV1 (0.41) | MAPTALDH1A1LMNAHTTTRPV1 | |
| SCHEMBL2230930 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL1645419 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL1127445 | 0.82 | TRPV1 (0.39) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL2229185 | 0.82 | MAPT (0.39) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL1126932 | 0.81 | MAPT (0.38) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL2231973 | 0.80 | MAPT (0.41) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL1127448 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL1126527 | 0.80 | MAPT (0.37) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL1647640 | 0.79 | MAPT (0.40) | MAPTALDH1A1LMNAHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |