Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127445 | 0.88 | TRPV1 (0.39) | ALDH1A1TSHRTRPV1MALT1KMT2A | |
| SCHEMBL1126898 | 0.88 | TRPV1 (0.41) | ALDH1A1KDRTRPV1MALT1MAPT | |
| SCHEMBL1127265 | 0.88 | KDR (0.37) | ALDH1A1TSHRKDRTRPV1MALT1 | |
| SCHEMBL1126932 | 0.86 | MAPT (0.38) | ALDH1A1TSHRKDRTRPV1MALT1 | |
| SCHEMBL1126527 | 0.85 | MAPT (0.37) | ALDH1A1TSHRTRPV1MAPTUSP2 | |
| SCHEMBL1127185 | 0.83 | MALT1 (0.37) | ALDH1A1TSHRTRPV1MALT1KMT2A | |
| SCHEMBL1127332 | 0.83 | MCHR1 (0.39) | ALDH1A1TRPV1MALT1MAPTHSD17B10 | |
| SCHEMBL1127209 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRKDRTRPV1KMT2A | |
| SCHEMBL1127076 | 0.82 | TRPV1 (0.38) | ALDH1A1TSHRTRPV1MALT1KMT2A | |
| SCHEMBL1126935 | 0.82 | GRIN2D (0.41) | ALDH1A1TSHRKMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |