Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19652083 | 0.86 | KDM1A (0.46) | KDM1AOPRD1FPR3FPR2KMT2A | |
| SCHEMBL3078179 | 0.85 | KMT2A (0.45) | KDM1AOPRD1FPR3FPR2MEN1 | |
| SCHEMBL19658763 | 0.84 | KDM1A (0.45) | KDM1AOPRD1FPR3FPR2KMT2A | |
| SCHEMBL19652089 | 0.83 | OPRD1 (0.48) | KDM1AOPRD1FPR3FPR2KMT2A | |
| SCHEMBL17753877 | 0.82 | KDM1A (0.48) | KDM1AOPRD1FPR3FPR2PDE8B | |
| SCHEMBL7524501 | 0.81 | KDM1A (0.46) | KDM1AOPRD1FPR3FPR2PDE8B | |
| SCHEMBL13853714 | 0.80 | OPRD1 (0.51) | KDM1AOPRD1FPR3FPR2PDE8B | |
| SCHEMBL27353435 | 0.80 | KDM1A (0.48) | KDM1AOPRD1FPR3FPR2KMT2A | |
| SCHEMBL1244838 | 0.79 | KDM1A (0.50) | KDM1AOPRD1FPR3FPR2PDE8B | |
| SCHEMBL5654694 | 0.79 | KDM1A (0.50) | KDM1AOPRD1FPR3FPR2PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2312947-B1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2014-01-01 | — | — | EP | disclosed |