Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18016698 | 0.91 | KMT2A (0.67) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL13514845 | 0.91 | KMT2A (0.45) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL234681 | 0.89 | ALDH1A1 (0.60) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL17051339 | 0.88 | TDP1 (0.51) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL6757523 | 0.85 | KMT2A (0.45) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL16199118 | 0.85 | ALDH1A1 (0.53) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL10259735 | 0.85 | TDP1 (0.54) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL15344079 | 0.85 | TDP1 (0.54) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL3148179 | 0.84 | TDP1 (0.67) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL17898603 | 0.83 | TDP1 (0.46) | KMT2ATSHRALDH1A1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359324-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-16 | — | — | US | disclosed |
| US-9051293-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | KMT2A 867/4885TSHR 1233/4885ALDH1A1 405/4885 |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | KMT2A 867/4885TSHR 1233/4885ALDH1A1 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.