SCHEMBL1647589

SCHEMBL1647589

O=C(O)c1ccc2c(c1)Cc1ccc(C(=O)O)cc1-2

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.79
MAPT P10636 3/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
SRD5A1 P18405 4/20 0.58
TDP2 O95551 2/20 0.57
ALDH1A1 P00352 3/20 0.55
HSD17B1 P14061 1/20 0.51
CYP1A2 P05177 1/20 0.50
HPGD P15428 1/20 0.50
DRD2 P14416 1/20 0.49
ADRA1D P25100 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR7 P34969 1/20 0.49
ADRA1A P35348 1/20 0.49
ADRA1B P35368 1/20 0.49
HTR2B P41595 1/20 0.49
TTR P02766 1/20 0.48
PTPRC P08575 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30976964 1.00 SRD5A2 (0.79) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL27506 0.94 SRD5A2 (0.81) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL31456551 0.94 SRD5A2 (0.81) SRD5A2MAPTNPC1RAB9ASRD5A1
Hydrochloric Acid SCHEMBL9789481 0.92 SRD5A2 (0.79) SRD5A2MAPTNPC1RAB9ASRD5A1
Phenol SCHEMBL29266727 0.90 SRD5A2 (0.76) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL3105349 0.89 SRD5A2 (0.86) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL29709873 0.89 SRD5A2 (0.86) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL31069845 0.89 SRD5A2 (0.86) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL503767 0.89 SRD5A2 (1.00) SRD5A2MAPTNPC1RAB9ASRD5A1
SCHEMBL29460235 0.89 SRD5A2 (1.00) SRD5A2MAPTNPC1RAB9ASRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180273463-A1 CATALYST HAVING A MODIFIED SILICON CARBIDE SUPPORT AND ITS USE AS A HYDROGENATION CATALYST UOP LLC (US) 2018-09-27 US claimed
US-8492583-B2 Hydrogenation using metal catalyst supported on heat, acid, abrasion and attrition resistant, high surface area silicon carbide support BP CORPORATION NORTH AMERICA INC. (US) 2013-07-23 US claimed
EP-1841724-B1 PROCESS FOR PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP CORP NORTH AMERICA INC (US) 2013-05-29 EP claimed
US-20080103333-A1 Process For Purification Of Aromatic Carboxylic Acids BP CORPORATION NORTH AMERICA INC. (US) 2008-05-01 US claimed
EP-1841724-A1 PROCESS FOR PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP Corporation North America Inc. (US) 2007-10-10 EP claimed
WO-2006071407-A1 PROCESS FOR PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP CORPORATION NORTH AMERICA INC. (US) 2006-07-06 WO claimed
US-4782181-A HYDROGENATION, CRYSTALLIZATION AMOCO CORPORATION (US) 1988-11-01 US claimed
CN-118253133-A PTA catalyst and phthalic acid recovery system and recovery method 南京惠若化工科技有限公司 2024-06-28 CN disclosed
US-20180273463-A1 CATALYST HAVING A MODIFIED SILICON CARBIDE SUPPORT AND ITS USE AS A HYDROGENATION CATALYST UOP LLC (US) 2018-09-27 US disclosed
WO-2017106298-A1 CATALYST HAVING A MODIFIED SILICON CARBIDE SUPPORT AND ITS USE AS A HYDROGENATION CATALYST UOP LLC (US) 2017-06-22 WO disclosed
CN-102421741-B Methods, steps and systems for treating, purifying crude terephthalic acid and related process streams INVISTA TECH SARL 2014-03-26 CN disclosed
US-8492583-B2 Hydrogenation using metal catalyst supported on heat, acid, abrasion and attrition resistant, high surface area silicon carbide support BP CORPORATION NORTH AMERICA INC. (US) 2013-07-23 US disclosed
EP-1841724-B1 PROCESS FOR PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP CORP NORTH AMERICA INC (US) 2013-05-29 EP disclosed
US-6765113-B2 CONTINUOUS OXIDATION OF PARAXYLENE BY OXYGEN IN SUPERCRITICAL WATER WITH MAGNESIUM BROMIDE CATALYST E.I. DU PONT DE NEMOURS AND COMPANY 2004-07-20 US disclosed
CN-1443152-A production of aromatic carboxylic acids DU PONT (US) 2003-09-17 CN disclosed
EP-1301456-A1 PRODUCTION OF AROMATIC CARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-16 EP disclosed
US-20020028968-A1 Production of aromatic carboxylic acids INVISTA NORTH AMERICA S.A.R.L. 2002-03-07 US disclosed
WO-2002006201-A1 PRODUCTION OF AROMATIC CARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-01-24 WO disclosed
US-4833269-A CATALYTIC HYDROGENATION AMOCO CORPORATION (US) 1989-05-23 US disclosed
US-4782181-A HYDROGENATION, CRYSTALLIZATION AMOCO CORPORATION (US) 1988-11-01 US disclosed