Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | TLR2 | O60603 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989790 | 0.84 | MEN1 (0.35) | MEN1KMT2ATSHRADRB2HTR1A | |
| SCHEMBL18313748 | 0.79 | MEN1 (0.49) | MEN1KMT2AADRB2HTR1ATLR2 | |
| SCHEMBL24602591 | 0.77 | MEN1 (0.44) | MEN1KMT2AADRB2HTR1ATLR2 | |
| SCHEMBL18313631 | 0.75 | MEN1 (0.41) | MEN1KMT2AADRB2HTR1ATLR2 | |
| SCHEMBL24602601 | 0.75 | MEN1 (0.41) | MEN1KMT2AADRB2HTR1ATLR2 | |
| SCHEMBL15697747 | 0.75 | MEN1 (0.42) | MEN1KMT2ATSHREPHX2POLB | |
| SCHEMBL23589933 | 0.74 | KMT2A (0.44) | MEN1KMT2AADRB2HTR1APOLB | |
| SCHEMBL23589931 | 0.74 | KMT2A (0.44) | MEN1KMT2AADRB2HTR1APOLB | |
| SCHEMBL14683542 | 0.74 | GLP1R (0.43) | MEN1KMT2ATSHREPHX2ALDH1A1 | |
| SCHEMBL18120321 | 0.73 | TLR2 (0.45) | TLR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629101-B2 | Cholesterol derivatives of inhibitors of viral fusion | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.R.L. (IT) | 2014-01-14 | — | — | US | disclosed |
| US-8629101-B2 | Cholesterol derivatives of inhibitors of viral fusion | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.R.L. (IT) | 2014-01-14 | — | — | US | disclosed |