Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 7/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313748 | 0.91 | MEN1 (0.49) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL23589931 | 0.85 | KMT2A (0.44) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL23589933 | 0.85 | KMT2A (0.44) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL24602591 | 0.85 | MEN1 (0.44) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL18313631 | 0.83 | MEN1 (0.41) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL16476478 | 0.75 | MEN1 (0.40) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL12989790 | 0.73 | MEN1 (0.35) | MEN1KMT2AADRB2HTR1APOLB | |
| SCHEMBL23589877 | 0.73 | GAA (0.52) | KMT2AGAAPOLBLMNAHPGD | |
| SCHEMBL23589953 | 0.71 | MEN1 (0.41) | MEN1KMT2AADRB2HTR1AGAA | |
| SCHEMBL23589878 | 0.70 | GAA (0.43) | MEN1KMT2AGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146865-A2 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2022-07-07 | — | — | WO | disclosed |