Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23589931 | 0.94 | KMT2A (0.44) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL23589933 | 0.94 | KMT2A (0.44) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL24602591 | 0.94 | MEN1 (0.44) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL18313631 | 0.91 | MEN1 (0.41) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL24602601 | 0.91 | MEN1 (0.41) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL23589877 | 0.80 | GAA (0.52) | KMT2AGAAPOLBSMN1; SMN2HPGD | |
| SCHEMBL16476478 | 0.79 | MEN1 (0.40) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL23589953 | 0.79 | MEN1 (0.41) | MEN1KMT2AGAAPOLBADRB2 | |
| SCHEMBL23589878 | 0.77 | GAA (0.43) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL16137445 | 0.77 | PTGS1 (0.38) | MEN1KMT2AGAAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2021-09-09 | — | — | US | disclosed |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY | 2018-06-14 | — | — | US | disclosed |
| WO-2016201007-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY (US) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, CRYZ | MEN1 220/4885KMT2A 3783/4885GAA 1155/4885 |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | MEN1 220/4885KMT2A 3783/4885GAA 1155/4885 |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | MEN1 220/4885KMT2A 3783/4885GAA 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.