⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25180895 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL8649236 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL2288494 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL28411413 | 0.73 | ALDH1A1 (0.63) | — | |
| SCHEMBL10025479 | 0.73 | — | — | |
| SCHEMBL28985652 | 0.73 | ALDH1A1 (0.57) | — | |
| SCHEMBL31590947 | 0.73 | — | — | |
| SCHEMBL2307497 | 0.70 | — | — | |
| SCHEMBL24496696 | 0.67 | TDP1 (0.41) | — | |
| SCHEMBL27876267 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789622-A | FXR regulator and preparation method and application thereof | 青岛睿吉医疗技术有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-119350422-B | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119350422-A | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-116789622-A | FXR regulator and preparation method and application thereof | 青岛睿吉医疗技术有限公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-2820013-A1 | LIVER X RECEPTOR (LXR) MODULATORS FOR THE TREATMENT OF DERMAL DISEASES, DISORDERS AND CONDITIONS | Alexar Therapeutics, Inc. (US) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013130892-A1 | LIVER X RECEPTOR (LXR) MODULATORS FOR THE TREATMENT OF DERMAL DISEASES, DISORDERS AND CONDITIONS | ANAYADERM, INC. (US) | 2013-09-06 | — | — | WO | disclosed |
| EP-2323697-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | Siemens Medical Solutions USA, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-2307421-A1 | OXINDOLE COMPOUNDS | Cylene Pharmaceuticals, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011964-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010002933-A1 | OXINDOLE COMPOUNDS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |