Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31283743 | 0.81 | DTYMK (0.64) | DTYMKCASP6TSHRALDH1A1KMT2A | |
| SCHEMBL3689029 | 0.81 | DTYMK (0.64) | DTYMKCASP6TSHRALDH1A1TDP1 | |
| SCHEMBL28134449 | 0.81 | DTYMK (0.64) | DTYMKCASP6TSHRALDH1A1KMT2A | |
| SCHEMBL130412 | 0.81 | DTYMK (0.64) | DTYMKCASP6TSHRALDH1A1TDP1 | |
| SCHEMBL263830 | 0.81 | CASP6 (0.72) | DTYMKCASP6TSHRTDP1LMNA | |
| SCHEMBL1851121 | 0.81 | CASP6 (0.72) | DTYMKCASP6TSHRTDP1LMNA | |
| SCHEMBL267752 | 0.81 | DTYMK (0.64) | DTYMKCASP6TSHRALDH1A1KMT2A | |
| SCHEMBL8187975 | 0.79 | DTYMK (0.62) | DTYMKCASP6TSHRALDH1A1TDP1 | |
| SCHEMBL275456 | 0.79 | DTYMK (0.62) | DTYMKCASP6TSHRALDH1A1TDP1 | |
| SCHEMBL268279 | 0.79 | DTYMK (0.62) | DTYMKCASP6TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483312-B1 | Antibodies that specifically bind to the EphA2 receptor | SANOFI SA (FR) | 2018-12-19 | — | — | EP | claimed |
| US-20150044197-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2015-02-12 | — | — | US | claimed |
| US-8668910-B2 | Antibodies that specifically bind to the EphA2 receptor | SANOFI (FR) | 2014-03-11 | — | — | US | claimed |
| US-20120201828-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-09 | — | — | US | claimed |
| EP-2483312-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-08 | — | — | EP | claimed |
| WO-2011039724-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | claimed |
| EP-2483312-B1 | Antibodies that specifically bind to the EphA2 receptor | SANOFI SA (FR) | 2018-12-19 | — | — | EP | disclosed |
| US-9676864-B2 | Antibodies that specifically bind to the EphA2 receptor | SANOFI (FR) | 2017-06-13 | — | — | US | disclosed |
| US-20150044197-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2015-02-12 | — | — | US | disclosed |
| US-8668910-B2 | Antibodies that specifically bind to the EphA2 receptor | SANOFI (FR) | 2014-03-11 | — | — | US | disclosed |
| US-20120201828-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-09 | — | — | US | disclosed |
| EP-2483312-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039724-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150044197-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | EPHA2, CD2BP2, EPHB2 | DTYMK 2141/4885CASP6 3071/4885TSHR 845/4885 |
| US-20120201828-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | EPHA2, CD2BP2, EPHB2 | DTYMK 2480/4885CASP6 2748/4885TSHR 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.