SCHEMBL267752

SCHEMBL267752

O=C(O)c1cc(O)ccc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 0.64
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
ALOX5 P09917 1/20 0.53
PTGS2 P35354 1/20 0.53
CASP6 P55212 1/20 0.52
BACE1 P56817 2/20 0.50
NPSR1 Q6W5P4 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.47
EGFR P00533 1/20 0.45
GPR35 Q9HC97 1/20 0.44
CDK2 P24941 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28134449 1.00 DTYMK (0.64) DTYMKCA12CA1CA2CA7
SCHEMBL31283743 1.00 DTYMK (0.64) DTYMKCA12CA1CA2CA7
SCHEMBL10831554 0.98 DTYMK (0.62) DTYMKCA12CA1CA2CA7
SCHEMBL6397073 0.98 DTYMK (0.62) DTYMKCA12CA1CA2CA7
SCHEMBL1663582 0.85 TSHR (0.53) DTYMKCA12CA1CA2CA7
SCHEMBL4456465 0.83 MAPT (0.52) DTYMKCASP6BACE1NPSR1RXFP1
Potassium Ion SCHEMBL10831551 0.83 BACE1 (0.49) DTYMKCASP6BACE1NPSR1RXFP1
SCHEMBL11367351 0.83 BACE1 (0.49) DTYMKCASP6BACE1NPSR1RXFP1
SCHEMBL6397059 0.83 BACE1 (0.49) DTYMKCA1CA2CASP6BACE1
SCHEMBL11282911 0.82 MEN1 (0.54) DTYMKCASP6BACE1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119286539-B Liquid crystal aligning agent and method for preparing high-hardness polyimide liquid crystal alignment film by using same 山东齐氟新材料有限公司 2025-03-21 CN claimed
CN-119286539-A Liquid crystal aligning agent and method for preparing high-hardness polyimide liquid crystal alignment film by using same 山东齐氟新材料有限公司 2025-01-10 CN claimed
CN-114292305-A Pharmaceutical co-crystal of progesterone and formic acid derivative and application thereof 国家卫生健康委科学技术研究所 2022-04-08 CN claimed
US-10626141-B2 Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence SHIMADZU CORPORATION (JP) 2020-04-21 US claimed
EP-2483312-B1 Antibodies that specifically bind to the EphA2 receptor SANOFI SA (FR) 2018-12-19 EP claimed
US-9932473-B2 Encapsulating resin composition, semiconductor device using the encapsulating resin composition, and method for manufacturing semiconductor device using the encapsulating resin composition PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2018-04-03 US claimed
EP-3246706-A1 METHOD FOR SPECIFIC CLEAVAGE OF C(ALPHA)-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE Shimadzu Corporation (JP) 2017-11-22 EP claimed
US-20170327533-A1 METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE SHIMADZU CORPORATION (JP) 2017-11-16 US claimed
EP-1390370-B1 METHODS FOR PREPARATION OF CYTOTOXIC CONJUGATES OF MAYTANSINOIDS AND CELL BINDING AGENTS IMMUNOGEN INC (US) 2016-04-13 EP claimed
US-20150044197-A1 ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR SANOFI (FR) 2015-02-12 US claimed
EP-1390370-A4 METHODS FOR PREPARATION OF CYTOTOXIC CONJUGATES OF MAYTANSINOIDS AND CELL BINDING AGENTS IMMUNOGEN INC (US) 2005-07-06 EP claimed
EP-1390370-A1 METHODS FOR PREPARATION OF CYTOTOXIC CONJUGATES OF MAYTANSINOIDS AND CELL BINDING AGENTS Immunogen, Inc. (US) 2004-02-25 EP claimed
US-20030055226-A1 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents IMMUNOGEN, INC. 2003-03-20 US claimed
WO-2002098883-A1 METHODS FOR PREPARATION OF CYTOTOXIC CONJUGATES OF MAYTANSINOIDS AND CELL BINDING AGENTS IMMUNOGEN, INC. (US) 2002-12-12 WO claimed
US-6441163-B1 COUPLING MAYTANSINOIDS HAVING DISULFIDE LINKER BEARING REACTIVE MOIETY TO SUCH AS ANTIBODIES WITHOUT PRIOR MODIFICATION OF SAID ANTIBODY; ONE-STEP, HIGH YIELD, LOWER COST IMMUNOGEN, INC. 2002-08-27 US claimed
EP-0304248-B1 CARBON DIOXIDE SENSOR Pfizer Hospital Products Group, Inc. (US) 1992-11-19 EP claimed
US-4851195-A FOR DETERMINING LIQUID PARTIAL PRESSURE; CONTAINING AN ABSORBER, A FLUORESCER AND BICARBONATE PFIZER HOSPITAL PRODUCTS GROUP, INC. (US) 1989-07-25 US claimed
EP-0024259-B1 DERIVATIVES OF 5-(PYRIDYL-2-OXY)-2-NITROBENZOIC ACID, THEIR PREPARATION AND HERBICIDAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1985-07-31 EP claimed
US-4469893-A Method for the preparation of nitrodiphenyl ethers OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-04 US claimed
EP-0024259-A1 Derivatives of 5-(pyridyl-2-oxy)-2-nitrobenzoic acid, their preparation and herbicidal compositions containing them CIBA-GEIGY AG (CH) 1981-02-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055226-A1 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents SPR, SELPLG, CD2BP2 DTYMK 565/4885CA12 728/4885CA1 1152/4885
US-20170327533-A1 METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE CPN1, CYBA, CRYAB DTYMK 3140/4885CA12 212/4885CA1 115/4885
US-10626141-B2 Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence CPN1, CYBA, CRYAB DTYMK 3140/4885CA12 212/4885CA1 115/4885
US-20150044197-A1 ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR EPHA2, CD2BP2, EPHB2 DTYMK 2141/4885CA12 829/4885CA1 1557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.