Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088048 | 0.92 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL3477565 | 0.83 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL9966179 | 0.82 | ALOX5 (0.53) | — | |
| SCHEMBL12927722 | 0.81 | ALOX5 (0.55) | — | |
| Trifluoroacetic Acid SCHEMBL29984059 | 0.80 | MCHR1 (0.50) | MCHR1 | |
| Trifluoroacetic Acid SCHEMBL27081951 | 0.80 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL21088049 | 0.80 | HTR2A (0.50) | MCHR1 | |
| SCHEMBL10154860 | 0.80 | HTR2A (0.65) | MCHR1 | |
| SCHEMBL15977193 | 0.75 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL21153968 | 0.74 | MCHR1 (0.53) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448585-B1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RES INC (US) | 2014-01-01 | — | — | EP | disclosed |