Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131362 | 0.90 | HTR2A (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL30704389 | 0.90 | HTR2A (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL31078590 | 0.89 | KDM4E (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL967629 | 0.81 | HTR2C (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL3927394 | 0.80 | HTR2A (0.67) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL30223611 | 0.80 | HTR2A (0.67) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL844491 | 0.80 | HTR2A (0.67) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL16477202 | 0.80 | MCHR1 (0.51) | MCHR1 | |
| Hydrochloric Acid SCHEMBL30396890 | 0.79 | KDM4E (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL9057430 | 0.79 | KDM4E (0.79) | HTR2AHTR2CKDM4EALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | BORISOVICH FROLOV YEVGENIY (RU) | 2012-02-16 | — | — | US | disclosed |
| EP-2062895-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008024029-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | ABCG2, HTR3C, AADAC | HTR2A 53/4885HTR2C 4/4885KDM4E 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.