Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | TTR | P02766 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836819 | 0.86 | MAOA (0.61) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL9837713 | 0.86 | MAOA (0.61) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL9218832 | 0.86 | NQO1 (0.48) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL21666688 | 0.84 | MAOA (0.78) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL172820 | 0.84 | MAOA (0.61) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL20329706 | 0.84 | NQO1 (0.47) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL41161 | 0.82 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL29398266 | 0.82 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL2354794 | 0.82 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL29358061 | 0.82 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | XDH, TYR, NISCH | MAOA 68/4885KDM4E 1101/4885ALDH1A1 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.