Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785027 | 0.88 | GAA (0.46) | TSHRGAAHTTPKMALDH1A1 | |
| SCHEMBL15339014 | 0.76 | TSHR (0.42) | TSHRTHRBHTTALDH1A1TDP1 | |
| SCHEMBL7922433 | 0.76 | HSP90AB1 (0.44) | TSHRTHRBHTTALDH1A1TDP1 | |
| SCHEMBL11298132 | 0.76 | THRB (0.46) | TSHRTHRBGAAHTTPKM | |
| SCHEMBL9315914 | 0.76 | TSHR (0.39) | TSHRTHRBHTTALDH1A1TDP1 | |
| SCHEMBL21705200 | 0.76 | ALDH1A1 (0.51) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL24325769 | 0.75 | ELANE (0.33) | TSHRALDH1A1 | |
| SCHEMBL11646076 | 0.75 | THRB (0.45) | TSHRTHRBGAAHTTPKM | |
| SCHEMBL11667997 | 0.75 | THRB (0.45) | TSHRTHRBGAAHTTPKM | |
| SCHEMBL14867062 | 0.74 | MEN1 (0.50) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |