Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785206 | 0.91 | GAA (0.57) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL784938 | 0.82 | GAA (0.57) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL16478411 | 0.81 | GAA (0.52) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL7196524 | 0.78 | GAA (0.59) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL20560119 | 0.77 | GAA (0.54) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11802510 | 0.77 | PTGS2 (0.62) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL28324794 | 0.77 | GAA (0.57) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9178091 | 0.76 | PTGS2 (0.61) | KMT2AALOX5PTGS1PTGS2MEN1 | |
| SCHEMBL9726973 | 0.76 | GAA (0.64) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL11520659 | 0.75 | GAA (0.68) | GAAKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |