Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478411 | 0.91 | GAA (0.52) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL785206 | 0.88 | GAA (0.57) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL7196524 | 0.83 | GAA (0.59) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL16478409 | 0.82 | GAA (0.52) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL11802510 | 0.81 | PTGS2 (0.62) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL9726973 | 0.80 | GAA (0.64) | GAAKMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL11520659 | 0.80 | GAA (0.68) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL28812143 | 0.79 | GAA (0.59) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL39122 | 0.79 | GAA (0.77) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL10466445 | 0.79 | GAA (0.51) | GAAKMT2AALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-8481670-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080311065-A1 | Anti-oxidant macromonomers and polymers and methods of making and using the same | POLNOX CORPORATION | 2008-12-18 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| WO-2007064843-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007050991-A1 | STABILIZED POLYOLEFIN COMPOSITIONS | POLNOX CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311065-A1 | Anti-oxidant macromonomers and polymers and methods of making and using the same | GPX4, LPO, GPX1 | GAA 2199/4885KMT2A 2526/4885ALOX5 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.