⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079989 | 0.78 | — | — | |
| SCHEMBL24505641 | 0.77 | — | — | |
| SCHEMBL668604 | 0.71 | — | — | |
| SCHEMBL8341889 | 0.71 | — | — | |
| SCHEMBL22438530 | 0.70 | ALDH1A1 (0.46) | — | |
| SCHEMBL12576581 | 0.69 | — | — | |
| SCHEMBL479385 | 0.67 | — | — | |
| SCHEMBL8844675 | 0.67 | — | — | |
| SCHEMBL28505755 | 0.67 | ALDH1A1 (0.54) | — | |
| SCHEMBL1649146 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8491929-B2 | Bioadhesive polymers | VAUNNEX INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-20110086095-A1 | Bioadhesive Polymers | Spherics, Inc (MA) | 2011-04-14 | — | — | US | disclosed |
| US-20100316712-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON'S DISEASE AND RELATED DISORDERS | COMBINATORX, INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| EP-2063867-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON'S DISEASE AND RELATED DISORDERS | Combinatorx, Incorporated (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080299204-A1 | Dosage forms for movement disorder treatment | SPHERICS, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| WO-2008079404-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON'S DISEASE AND RELATED DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080131492-A1 | Dosage forms for movement disorder treatment | SPHERICS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1901720-A2 | IMPROVED DOSAGE FORMS FOR MOVEMENT DISORDER TREATMENT | Spherics, Inc. (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2008002471-A2 | EROSION-STABILIZED BIOADHESIVE POLYMERS FUNCTIONALIZED OR BLENDED WITH CATECHOL AND DERIVATIVES THEREOF | SPHERICS, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20070148238-A1 | Dosage forms for movement disorder treatment | SPHERICS, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| WO-2007002318-A2 | BIOADHESIVE POLYMERS | SPHERICS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007002516-A2 | IMPROVED DOSAGE FORMS FOR MOVEMENT DISORDER TREATMENT | SPHERICS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20070003621-A1 | Dosage forms for movement disorder treatment | SPHERICS, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |