⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423505 | 0.83 | — | — | |
| SCHEMBL1649146 | 0.77 | — | — | |
| SCHEMBL4637059 | 0.75 | — | — | |
| SCHEMBL8341889 | 0.75 | — | — | |
| SCHEMBL27333582 | 0.75 | CES1 (0.50) | — | |
| SCHEMBL479385 | 0.71 | — | — | |
| SCHEMBL1014297 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL9684944 | 0.69 | LMNA (0.50) | — | |
| SCHEMBL9003710 | 0.69 | GAA (0.31) | — | |
| SCHEMBL3748077 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594770-B | Construction of rheumatoid arthritis therapeutic vaccine aiming at human TNF alpha molecules | 上海惠盾因泰生物科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115594770-A | Construction of rheumatoid arthritis therapeutic vaccine aiming at human TNF alpha molecules | 上海惠盾因泰生物科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| EP-2249873-B1 | CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO A POLYANION FOR THE TREATMENT OF AIDS | PASTEUR INSTITUT (FR) | 2016-11-16 | — | — | EP | claimed |
| EP-2478049-B1 | A POLYMER SUPPORT | UNIV CAPE TOWN (ZA) | 2015-02-25 | — | — | EP | claimed |
| US-20090203842-A1 | Macromolecular Conjugates And Processes For Preparing The Same | ABBOTT LABORATORIES (US) | 2009-08-13 | — | — | US | claimed |
| EP-1478927-A4 | MACROMOLECULAR CONJUGATES AND PROCESSES FOR PREPARING SAME | ABBOTT LAB (US) | 2008-07-30 | — | — | EP | claimed |
| EP-1478927-A2 | MACROMOLECULAR CONJUGATES AND PROCESSES FOR PREPARING SAME | Abbott Laboratories (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072017-A2 | MACROMOLECULAR CONJUGATES AND PROCESSES FOR PREPARING SAME | ABBOTT LABORATORIES (US) | 2003-09-04 | — | — | WO | claimed |
| US-20030149246-A1 | Macromolecular conjugates and processes for preparing the same | ABBOTT LABORATORIES | 2003-08-07 | — | — | US | claimed |
| JP-61007250-A | — | — | None | — | — | JP | disclosed |
| US-20240157022-A1 | Polyphosphate-Functionalized Inorganic Nanoparticles as Hemostatic Compositions and Methods of Use | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2024-05-16 | — | — | US | disclosed |
| WO-2024092126-A1 | COMPOSITIONS AND METHODS FOR IMPROVED IMMUNOTHERAPIES | CARGO THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| EP-4360656-A2 | POLYPHOSPHATE-FUNCTIONALIZED INORGANIC NANOPARTICLES AS HEMOSTATIC COMPOSITIONS AND METHODS OF USE | The Regents of The University of California (US) | 2024-05-01 | — | — | EP | disclosed |
| EP-3659627-B1 | POLYPHOSPHATE-FUNCTIONALIZED INORGANIC NANOPARTICLES AS HEMOSTATIC COMPOSITIONS AND METHODS OF USE | UNIV CALIFORNIA (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20030149246-A1 | Macromolecular conjugates and processes for preparing the same | ABBOTT LABORATORIES | 2003-08-07 | — | — | US | disclosed |
| US-6514773-B1 | Immunoassay; detection of controlled substances on surfaces; test kits | SECURETEC DETEKTIONS-SYSTEME AG (DE) | 2003-02-04 | — | — | US | disclosed |
| US-20020025312-A1 | BIFUNCTIONAL WATER-SOLUBLE POLYMER DERIVATIVE AND COMPLEX CONTAINING IT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| US-6177259-B1 | SCREENING FOR INHIBITORS BY INCUBATING CASPASE, POLYGLUTAMINE PEPTIDE, AND CANDIDATE WHERE REDUCTION IN COMPLEX FORMATION INDICATES INHIBITOR; TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS HUNTINGTON'S DISEASE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-01-23 | — | — | US | disclosed |
| EP-0903152-A2 | Bifunctional water-soluble polymer derivative and complex containing it | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |
| JP-S617250-A | S-ACETYLTHIOPROPIONIC ACID DERIVATIVE | SUMITOMO CHEM CO LTD | 1986-01-13 | — | — | JP | disclosed |