Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480261 | 0.79 | HDAC6 (0.41) | MEN1POLBTSHRKMT2ATDP1 | |
| SCHEMBL16480262 | 0.76 | HDAC6 (0.42) | MEN1POLBGAAKMT2ATDP1 | |
| SCHEMBL23964219 | 0.75 | HDAC6 (0.48) | MEN1ALDH1A1POLBGAATSHR | |
| SCHEMBL16480266 | 0.73 | MEN1 (0.42) | MEN1ALDH1A1POLBGAAHPGD | |
| SCHEMBL23775122 | 0.73 | HDAC6 (0.46) | MEN1ALDH1A1POLBGAATSHR | |
| SCHEMBL16480252 | 0.73 | MEN1 (0.41) | MEN1ALDH1A1POLBTSHRKMT2A | |
| SCHEMBL17234849 | 0.71 | KDM4E (0.57) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL16480246 | 0.71 | HDAC6 (0.38) | MEN1POLBGAAKMT2ATDP1 | |
| SCHEMBL19849746 | 0.68 | KDM4E (0.58) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL17231310 | 0.68 | KDM4E (0.56) | DHFRKDM4EMEN1ALDH1A1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181375-B2 | Fluorescent potassium ion sensors | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizo (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | KCNN1, KCNN2, KCNN3 | DHFR 4772/4885KDM4E 2479/4885MEN1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.