Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480262 | 0.88 | HDAC6 (0.42) | HDAC6HDAC8HDAC10HDAC3HDAC1 | |
| SCHEMBL16480267 | 0.86 | MEN1 (0.42) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL16480266 | 0.86 | MEN1 (0.42) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL16480252 | 0.86 | MEN1 (0.41) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL23964219 | 0.85 | HDAC6 (0.48) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL16480246 | 0.83 | HDAC6 (0.38) | HDAC6HDAC8HDAC10HDAC3HDAC1 | |
| SCHEMBL23775122 | 0.81 | HDAC6 (0.46) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL16480243 | 0.79 | DHFR (0.34) | HDAC6HDAC8HDAC10HDAC3HDAC1 | |
| SCHEMBL16480253 | 0.79 | MEN1 (0.37) | HDAC6HDAC8HDAC10RAB9AHDAC3 | |
| SCHEMBL16480260 | 0.78 | ITGB3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181375-B2 | Fluorescent potassium ion sensors | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizo (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | KCNN1, KCNN2, KCNN3 | HDAC6 3054/4885HDAC8 3694/4885HDAC10 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.