Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893103 | 0.82 | NSD2 (0.45) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL9891737 | 0.82 | NSD2 (0.45) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL16480373 | 0.82 | POLB (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6984473 | 0.80 | NOTUM (0.53) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL9105102 | 0.80 | NOTUM (0.53) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL16480394 | 0.79 | KMT2A (0.48) | ALOX5NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7123162 | 0.79 | NOTUM (0.46) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL7123171 | 0.79 | NOTUM (0.46) | FADS1NSD2ALOX5NOTUMDRD2 | |
| SCHEMBL16480422 | 0.78 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL1937222 | 0.78 | DDB1 (0.44) | GRM2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |