Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480426 | 0.88 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3PKMALDH1A1 | |
| SCHEMBL16480476 | 0.88 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL16480395 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9893163 | 0.82 | CCR1 (0.45) | SLC6A2SLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9108353 | 0.81 | KMT2A (0.51) | PKMALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9891770 | 0.81 | PKM (0.46) | SLC6A2SLC6A4SLC6A3PKMALDH1A1 | |
| SCHEMBL9108362 | 0.81 | KMT2A (0.51) | PKMALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL16480372 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ABL1 | |
| SCHEMBL13934938 | 0.80 | AR (0.62) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22658820 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384320-B1 | PYRROLIDINE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |