Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254904 | 0.95 | HPGD (0.46) | CNR2GAAHPGDLIPEALDH1A1 | |
| SCHEMBL28816840 | 0.79 | HPGD (0.52) | GAAHPGDLIPEALDH1A1 | |
| SCHEMBL27873611 | 0.79 | HPGD (0.52) | GAAHPGDLIPEALDH1A1 | |
| SCHEMBL4021879 | 0.79 | HPGD (0.52) | GAAHPGDLIPEALDH1A1 | |
| SCHEMBL9893028 | 0.79 | CNR2 (0.44) | CNR2ALDH1A1 | |
| SCHEMBL9891849 | 0.79 | CNR2 (0.46) | CNR2LIPEALDH1A1 | |
| SCHEMBL16255148 | 0.78 | HPGD (0.53) | GAAHPGDLIPEALDH1A1 | |
| SCHEMBL9107274 | 0.78 | CNR2 (0.48) | CNR2 | |
| SCHEMBL8520605 | 0.77 | CA2 (0.50) | GAAHPGDLIPEALDH1A1ACKR3 | |
| SCHEMBL16480463 | 0.77 | MEN1 (0.50) | CNR2GAAHPGDLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |