Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254877 | 0.95 | MEN1 (0.48) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL4021879 | 0.80 | HPGD (0.52) | MEN1KMT2ASMN1; SMN2MAPTRECQL | |
| SCHEMBL27873611 | 0.80 | HPGD (0.52) | MEN1KMT2ASMN1; SMN2MAPTRECQL | |
| SCHEMBL28816840 | 0.80 | HPGD (0.52) | MEN1KMT2ASMN1; SMN2MAPTRECQL | |
| SCHEMBL16255148 | 0.79 | HPGD (0.53) | SMN1; SMN2RECQLGAAHPGDLIPE | |
| SCHEMBL8520605 | 0.79 | CA2 (0.50) | SMN1; SMN2GAAHPGDL3MBTL1LIPE | |
| SCHEMBL9891865 | 0.78 | MEN1 (0.46) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9893038 | 0.78 | MEN1 (0.46) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16480409 | 0.77 | CNR2 (0.44) | CNR2GAAHPGDLIPE | |
| SCHEMBL3708847 | 0.77 | MEN1 (0.48) | MEN1TP53KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |