Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891749 | 0.80 | CYP2D6 (0.34) | L3MBTL1CYP2D6CHRNA7SRD5A1NOTUM | |
| SCHEMBL9893008 | 0.80 | NOTUM (0.35) | L3MBTL1CYP2D6CHRNA7SRD5A1NOTUM | |
| SCHEMBL9110142 | 0.77 | MMP8 (0.43) | L3MBTL1CYP2D6CHRNA7CNR2 | |
| SCHEMBL9107566 | 0.77 | MMP8 (0.43) | L3MBTL1CYP2D6CHRNA7CNR2 | |
| SCHEMBL9893145 | 0.71 | SLC6A2 (0.46) | L3MBTL1SRD5A1NOTUMSLC6A2SLC6A4 | |
| SCHEMBL22658820 | 0.71 | SLC6A2 (0.46) | L3MBTL1SRD5A1NOTUMSLC6A2SLC6A4 | |
| SCHEMBL9893029 | 0.69 | GAA (0.44) | CYP2D6SRD5A1NOTUMCNR2 | |
| SCHEMBL16098324 | 0.68 | ROCK1 (0.37) | PER2 | |
| SCHEMBL16480394 | 0.68 | KMT2A (0.48) | NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16480476 | 0.68 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |