Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480417 | 0.80 | L3MBTL1 (0.37) | NOTUMCYP2D6CHRNA7PER2SRD5A1 | |
| SCHEMBL9891749 | 0.77 | CYP2D6 (0.34) | NOTUMCYP2D6CHRNA7SRD5A1PTGER2 | |
| SCHEMBL9107566 | 0.73 | MMP8 (0.43) | CYP2D6CHRNA7L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9110142 | 0.73 | MMP8 (0.43) | CYP2D6CHRNA7L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9892975 | 0.70 | PTGER2 (0.44) | NOTUMSRD5A1PTGER2PTGER3PTGDR | |
| SCHEMBL9893157 | 0.68 | PTGER2 (0.42) | PER2PTGER2PTGER3PTGDRPTGER1 | |
| SCHEMBL9893023 | 0.68 | PER2 (0.46) | PER2PTGER2PTGER3PTGDRKDM4E | |
| SCHEMBL9893095 | 0.68 | NOTUM (0.50) | NOTUMPER2SRD5A1BRD4 | |
| SCHEMBL16691753 | 0.68 | MAP4K1 (0.39) | NOTUMPER2PTGER2PTGER3PTGDR | |
| SCHEMBL9892976 | 0.66 | PTGER2 (0.41) | PER2PTGER2PTGER3PTGDRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | NOTUM 2241/4885CYP2D6 1472/4885CHRNA7 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.