SCHEMBL1648129

SCHEMBL1648129

Brc1ccc(CCSSCCc2ccc(Br)cc2Br)c(Br)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.40
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.37
HSP90AA1 P07900 1/20 0.37
TLR9 Q9NR96 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AHR P35869 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10831466 0.77 PYCR1 (0.42) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL4798355 0.76 ALOX15 (0.44) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL18378343 0.76 HSP90AA1 (0.43) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL11451577 0.76 PYCR1 (0.44) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL18378296 0.76 PYCR1 (0.41) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL7955333 0.74 ALOX15 (0.46) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL1648557 0.73 TAAR1 (0.58) PYCR1TSHRLMNATAAR1
SCHEMBL18242441 0.72 PYCR1 (0.39) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL18241859 0.72 HSP90AA1 (0.40) PYCR1ALOX15MAPK1HSP90AA1TLR9
SCHEMBL31108182 0.72 TYR (0.46) PYCR1ALOX15MAPK1HSP90AA1TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed