SCHEMBL16481440

SCHEMBL16481440

N#Cc1ccc(Nc2cccc(C#N)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
MAPT P10636 3/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CDC7 O00311 1/20 0.55
KCNA5 P22460 1/20 0.51
SLC2A1 P11166 1/20 0.51
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
ABCG2 Q9UNQ0 6/20 0.49
ABCB1 P08183 3/20 0.49
IDO1 P14902 1/20 0.49
SYK P43405 1/20 0.48
ABCC1 P33527 1/20 0.47
AR P10275 1/20 0.46
FLT1 P17948 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL953597 0.92 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL6156438 0.90 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL15145204 0.87 ALDH1A1 (0.53) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL16481157 0.87 CDC7 (0.71) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL24809296 0.85 ABCG2 (0.55) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL15455464 0.85 CDC7 (0.49) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL5461991 0.83 MAOB (0.52) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL10567345 0.83 ABCG2 (0.57) ALDH1A1MAPTMEN1KMT2ACDC7
SCHEMBL9481712 0.83 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL510240 0.83 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014058232-A2 SPIRO-TYPE ORGANIC MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 대주전자재료 주식회사 (KR) 2014-04-17 WO disclosed