SCHEMBL953597

SCHEMBL953597

N#Cc1cccc(Nc2cccc(C#N)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
IDO1 P14902 1/20 0.55
ABCG2 Q9UNQ0 4/20 0.54
KCNA5 P22460 1/20 0.53
CDC7 O00311 1/20 0.53
SYK P43405 1/20 0.53
FLT1 P17948 1/20 0.50
FLT4 P35916 1/20 0.50
KDR P35968 1/20 0.50
SLC2A1 P11166 1/20 0.49
HTT P42858 1/20 0.49
LMNA P02545 1/20 0.49
AR P10275 1/20 0.48
EGFR P00533 1/20 0.48
STK10 O94804 1/20 0.48
SLK Q9H2G2 1/20 0.48
GRM4 Q14833 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156438 0.94 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL16481440 0.92 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL30619678 0.88 NPSR1 (0.60) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL21439863 0.88 NPSR1 (0.60) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL15455464 0.88 CDC7 (0.49) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL16481157 0.87 CDC7 (0.71) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL10567345 0.87 ABCG2 (0.57) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL15145204 0.87 ALDH1A1 (0.53) ALDH1A1MAPTMEN1KMT2AIDO1
SCHEMBL24809296 0.85 ABCG2 (0.55) ALDH1A1MAPTMEN1KMT2AABCG2
SCHEMBL1981048 0.85 ABCG2 (0.51) ALDH1A1MAPTABCG2CDC7SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014058232-A2 SPIRO-TYPE ORGANIC MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 대주전자재료 주식회사 (KR) 2014-04-17 WO disclosed
US-8273677-B2 Production process of pre-polymerized polymerization catalyst component and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-20110245438-A1 PRODUCTION PROCESS OF PRE-POLYMERIZED POLYMERIZATION CATALYST COMPONENT AND ADDITION POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed
US-7932330-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-7872080-B2 Processes for producing a catalyst component for addition polymerization, a catalyst and an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-18 US disclosed
US-20110009579-A1 Processes For Producing A Catalyst Component For Addition Polymerization, A Catalyst And An Addition Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-7592402-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-22 US disclosed
US-20090227746-A1 Processes for producing a catalyst component for addition polymerization, a catalyst and an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-10 US disclosed
US-7524789-B2 Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-28 US disclosed
EP-1325934-A1 Modified particles, carrier prepared therefrom, catalyst component for olefin polymerization prepared therefrom, catalyst for olefin polymerization prepared therefrom, and method for producing olefin polymer Sumitomo Chemical Company, Limited (JP) 2003-07-09 EP disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
EP-0949273-B1 MODIFIED PARTICLES, CARRIER PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST COMPONENT PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST PREPARED THEREFROM, AND PROCESS FOR PREPARING OLEFIN POLYMER SUMITOMO CHEMICAL CO (JP) 2003-04-02 EP disclosed
US-6482765-B1 Modified particles, carrier prepared therefrom, olefin polymerization catalyst component prepared therefrom, olefin polymerization catalyst prepared therefrom, and process for preparing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-19 US disclosed
US-20020143124-A1 Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-03 US disclosed
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
US-6284699-B1 COORDINATION POLYMERIZATION CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-04 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0949273-A1 MODIFIED PARTICLES, CARRIER PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST COMPONENT PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST PREPARED THEREFROM, AND PROCESS FOR PREPARING OLEFIN POLYMER Sumitomo Chemical Company, Limited (JP) 1999-10-13 EP disclosed