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SCHEMBL16482160

SCHEMBL16482160

c1cc(-c2ccc3sc4ccccc4c3c2)cc(-n2c3cc(-n4c5ccccc5c5ccccc54)ccc3c3c4sc5ccccc5c4ccc32)c1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ MAPT P10636 2/20 0.31
▸ RXFP1 Q9HBX9 1/20 0.31
▸ LIMK1 P53667 1/20 0.30
▸ TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16482350 0.95 ALOX5 (0.34) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL16482174 0.95 KDM4E (0.36) ALOX5KDM4EATML3MBTL1LIMK1
SCHEMBL16484442 0.94 ALOX5 (0.33) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL16482212 0.92 ATM (0.38) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL16482092 0.91 L3MBTL1 (0.40) KDM4EATML3MBTL1MAPTLIMK1
SCHEMBL16482480 0.91 KDM4E (0.37) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL24676246 0.91 KDM4E (0.39) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL24675459 0.91 KDM4E (0.39) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL24676345 0.91 KDM4E (0.39) ALOX5KDM4EATML3MBTL1MAPT
SCHEMBL24676263 0.91 KDM4E (0.39) ALOX5KDM4EATML3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014057659-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME 出光興産株式会社 (JP) 2014-04-17 — — WO disclosed