SCHEMBL16482245

SCHEMBL16482245

c1cc(-c2ccc3oc4ccccc4c3c2)cc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3c4oc5ccccc5c4ccc32)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.34
KDM4E B2RXH2 3/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PLA2G10 O15496 1/20 0.33
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RXFP1 Q9HBX9 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17807313 0.96 KDM4E (0.38) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL17807314 0.96 ALOX5 (0.33) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL16482244 0.95 ALOX5 (0.34) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL17807309 0.95 ALOX5 (0.34) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL16484534 0.94 PLA2G2A (0.36) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL16641322 0.94 KDM4E (0.40) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL16482183 0.94 PLA2G2A (0.38) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL24077372 0.94 ALOX5 (0.36) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL15337995 0.94 KDM4E (0.39) ALOX5KDM4EPLA2G2APLA2G4AATM
SCHEMBL16485650 0.94 PLA2G2A (0.39) ALOX5KDM4EPLA2G2APLA2G4AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014057659-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed