Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483412 | 0.94 | MET (0.52) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12777044 | 0.89 | MET (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL16484906 | 0.86 | MET (0.53) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL16483464 | 0.84 | MET (0.51) | NPC1RAB9AMEN1KMT2AHSD17B10 | |
| SCHEMBL4544648 | 0.83 | HSD17B10 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12776881 | 0.82 | HPGD (0.49) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12776920 | 0.81 | ALDH1A1 (0.54) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12777051 | 0.81 | MET (0.55) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL16484903 | 0.81 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL19768434 | 0.81 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |