Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483375 | 0.97 | TNF (0.43) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL16483356 | 0.92 | DYRK1A (0.39) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL15480167 | 0.92 | KDM4E (0.39) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL15480172 | 0.92 | KDM4E (0.39) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL16483839 | 0.89 | MAOA (0.41) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL16483422 | 0.88 | TNF (0.42) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL25208637 | 0.88 | L3MBTL1 (0.50) | KDM4EATML3MBTL1DUSP3MAPK14 | |
| SCHEMBL31003063 | 0.88 | L3MBTL1 (0.50) | KDM4EATML3MBTL1DUSP3MAPK14 | |
| SCHEMBL16483591 | 0.88 | MAOA (0.40) | MAOAMAOBACHETNFKDM4E | |
| SCHEMBL16483548 | 0.87 | TNF (0.40) | MAOAMAOBACHETNFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |