Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483387 | 0.91 | TNF (0.36) | TNFDYRK1AKDM4ECDK4CCND1 | |
| SCHEMBL16483426 | 0.91 | TNF (0.45) | TNFDYRK1AALDH1A1HPGDKDM4E | |
| SCHEMBL16484883 | 0.90 | TNF (0.43) | TNFDYRK1AALDH1A1HPGDKDM4E | |
| SCHEMBL16483163 | 0.89 | TNF (0.40) | TNFDYRK1AALDH1A1HPGDKDM4E | |
| SCHEMBL16483438 | 0.89 | TNF (0.45) | TNFDYRK1AKDM4EGFERNPSR1 | |
| SCHEMBL17341213 | 0.87 | L3MBTL1 (0.37) | TNFALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL16483356 | 0.86 | DYRK1A (0.39) | TNFDYRK1AKDM4EKCNH2CDK4 | |
| SCHEMBL16483406 | 0.86 | TNF (0.41) | TNFDYRK1AALDH1A1HPGDKDM4E | |
| SCHEMBL17341424 | 0.86 | L3MBTL1 (0.39) | TNFALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16483354 | 0.84 | TNF (0.39) | TNFDYRK1AALDH1A1HPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |