Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483590 | 0.90 | TNF (0.39) | TNFCDK4CDK6DYRK1AHASPIN | |
| SCHEMBL16483363 | 0.90 | HASPIN (0.41) | TNFHASPINL3MBTL1AOC3TDO2 | |
| SCHEMBL16483348 | 0.90 | HASPIN (0.41) | TNFHASPINL3MBTL1AOC3TDO2 | |
| SCHEMBL16484905 | 0.90 | TNF (0.40) | TNFCDK4CDK6DYRK1AMAPK8 | |
| SCHEMBL16483356 | 0.88 | DYRK1A (0.39) | TNFCDK4CDK6DYRK1AL3MBTL1 | |
| SCHEMBL17341426 | 0.88 | ALDH1A1 (0.42) | ALKALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL17341226 | 0.87 | L3MBTL1 (0.40) | ALKALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL15480166 | 0.86 | DYRK1A (0.39) | TNFCDK4CDK6DYRK1AALK | |
| SCHEMBL15480168 | 0.86 | DYRK1A (0.39) | TNFCDK4CDK6DYRK1AALK | |
| SCHEMBL16483544 | 0.84 | DYRK1A (0.40) | TNFCDK4CDK6DYRK1AALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |