Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483479 | 0.95 | PIK3CA (0.39) | TNFPIK3CAMAPTCYP11B1CYP11B2 | |
| SCHEMBL16483512 | 0.94 | TNF (0.38) | TNFPIK3CAIMPDH2ALKALOX5 | |
| SCHEMBL16483454 | 0.94 | TNF (0.44) | TNFALOX5MEN1HSP90AA1MAPT | |
| SCHEMBL16484870 | 0.93 | TNF (0.36) | TNFPIK3CAIMPDH2ALKALOX5 | |
| SCHEMBL16483422 | 0.92 | TNF (0.42) | TNFALOX5KMT2ACYP11B1CYP11B2 | |
| SCHEMBL16484873 | 0.91 | TNF (0.38) | TNFALOX5CYP11B1CYP11B2CDC7 | |
| SCHEMBL16483495 | 0.90 | TNF (0.43) | TNFALKALOX5MEN1HSP90AA1 | |
| SCHEMBL16483433 | 0.90 | TNF (0.40) | TNFALOX5MEN1HSP90AA1MAPT | |
| SCHEMBL16483480 | 0.89 | TNF (0.40) | TNFALOX5KMT2ACYP11B1CYP11B2 | |
| SCHEMBL16483548 | 0.88 | TNF (0.40) | TNFPIK3CAALKMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |