Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16484885 | 0.95 | TNF (0.35) | TNFPIK3CADYRK1ACDK4CDK6 | |
| SCHEMBL16483728 | 0.93 | KDM4E (0.35) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16483431 | 0.93 | TNF (0.39) | TNFPIK3CADYRK1AIMPDH2ALK | |
| SCHEMBL16484857 | 0.93 | TNF (0.39) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16484912 | 0.93 | TNF (0.41) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16483433 | 0.91 | TNF (0.40) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16484858 | 0.90 | TNF (0.36) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16484909 | 0.90 | TNF (0.37) | TNFDYRK1ACDK4CDK6ALOX5 | |
| SCHEMBL16484905 | 0.89 | TNF (0.40) | TNFDYRK1ACDK4CDK6ALK | |
| SCHEMBL16483512 | 0.89 | TNF (0.38) | TNFPIK3CAIMPDH2ALKALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |