Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16484905 | 0.92 | TNF (0.40) | TNFHASPINALOX5TDO2PIK3CD | |
| SCHEMBL16483454 | 0.92 | TNF (0.44) | TNFALOX5CDC7CDK2MEN1 | |
| SCHEMBL16483153 | 0.91 | HASPIN (0.44) | TNFHASPINALOX5TDO2PIK3CD | |
| SCHEMBL16484873 | 0.91 | TNF (0.38) | TNFALOX5CDC7CDK2 | |
| SCHEMBL16483431 | 0.90 | TNF (0.39) | TNFHASPINALOX5CDC7CDK2 | |
| SCHEMBL16483422 | 0.90 | TNF (0.42) | TNFALOX5CDC7CDK2KMT2A | |
| SCHEMBL16483433 | 0.88 | TNF (0.40) | TNFALOX5CDC7CDK2DGAT2 | |
| SCHEMBL16483479 | 0.87 | PIK3CA (0.39) | TNFMAPT | |
| SCHEMBL16483432 | 0.87 | MAPK9 (0.38) | TNFTDO2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483480 | 0.87 | TNF (0.40) | TNFALOX5CDC7CDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |