Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483503 | 0.88 | KDM4E (0.44) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL19768505 | 0.81 | KDM4E (0.43) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL19768465 | 0.81 | CLK1 (0.42) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL16483530 | 0.80 | KDM4E (0.38) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL19768509 | 0.80 | CYP11B1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16483782 | 0.79 | MAPT (0.41) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL16483793 | 0.79 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL16483028 | 0.79 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL19768447 | 0.79 | CYP19A1 (0.50) | MAPTKDM4EALDH1A1CYP1A2CYP1A1 | |
| SCHEMBL16483656 | 0.78 | TNF (0.48) | MAPTKDM4EALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |