Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483503 | 0.88 | KDM4E (0.44) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL28124903 | 0.82 | ALDH1A1 (0.40) | KDM4EL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL16483028 | 0.82 | ALDH1A1 (0.40) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16483793 | 0.82 | ALDH1A1 (0.40) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16483473 | 0.80 | MAPT (0.41) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL12269043 | 0.80 | ALDH1A1 (0.40) | KDM4EL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL16483782 | 0.79 | MAPT (0.41) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16483327 | 0.79 | NPC1 (0.40) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16483031 | 0.79 | CDK2 (0.45) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL16483278 | 0.79 | NPC1 (0.50) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |