Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483495 | 0.92 | TNF (0.43) | TNFHASPINCDK4CDK6ALOX5 | |
| SCHEMBL16484912 | 0.92 | TNF (0.41) | TNFCDK4CDK6DYRK1AALOX5 | |
| SCHEMBL16483153 | 0.91 | HASPIN (0.44) | TNFHASPINALOX5TDO2PIK3CD | |
| SCHEMBL16484858 | 0.91 | TNF (0.36) | TNFCDK4CDK6DYRK1AALOX5 | |
| SCHEMBL16484857 | 0.90 | TNF (0.39) | TNFCDK4CDK6DYRK1AALOX5 | |
| SCHEMBL16483354 | 0.90 | TNF (0.39) | TNFHASPINCDK4CDK6DYRK1A | |
| SCHEMBL16484870 | 0.89 | TNF (0.36) | TNFCDK4CDK6DYRK1AALOX5 | |
| SCHEMBL16483433 | 0.88 | TNF (0.40) | TNFCDK4CDK6DYRK1AALOX5 | |
| SCHEMBL16484866 | 0.87 | PIK3CD (0.36) | TNFDYRK1ATDO2PIK3CDPIK3CB | |
| SCHEMBL16484909 | 0.87 | TNF (0.37) | TNFCDK4CDK6DYRK1AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |