Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16484883 | 0.92 | TNF (0.43) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483174 | 0.92 | TNF (0.45) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483156 | 0.90 | TNF (0.38) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483426 | 0.90 | TNF (0.45) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483454 | 0.90 | TNF (0.44) | TNFMAPTKDM4ECDC7CDK2 | |
| SCHEMBL16483422 | 0.88 | TNF (0.42) | TNFKDM4ECDC7CDK2ALOX5 | |
| SCHEMBL16483496 | 0.87 | TNF (0.44) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483495 | 0.86 | TNF (0.43) | TNFMAPTCDC7CDK2ALOX5 | |
| SCHEMBL16483511 | 0.86 | TNF (0.38) | TNFMAPTALDH1A1HPGDCDC7 | |
| SCHEMBL16483431 | 0.86 | TNF (0.39) | TNFMAPTCDC7CDK2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |