Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483146 | 0.97 | NTSR1 (0.36) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483567 | 0.95 | TNF (0.35) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483859 | 0.94 | TNF (0.37) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483826 | 0.93 | TNF (0.36) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483823 | 0.93 | TNF (0.36) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483682 | 0.92 | TNF (0.42) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483144 | 0.89 | TNF (0.41) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL17341522 | 0.89 | TLR4 (0.34) | NTSR1MAPTKMT2A | |
| SCHEMBL16483695 | 0.88 | NTSR1 (0.37) | NTSR1TNFPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483593 | 0.88 | TNF (0.34) | NTSR1TNFPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |