Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483144 | 0.97 | TNF (0.41) | TNFMAPK10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483551 | 0.95 | TNF (0.43) | TNFMAPK10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483671 | 0.92 | NTSR1 (0.36) | TNFPIK3CDPIK3CBPIK3CGMAPT | |
| SCHEMBL16483146 | 0.89 | NTSR1 (0.36) | TNFPIK3CDPIK3CBPIK3CGMAPT | |
| SCHEMBL17341522 | 0.89 | TLR4 (0.34) | MAPTTLR4NTSR1KMT2A | |
| SCHEMBL16483673 | 0.88 | TNF (0.43) | TNFMAPK10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483584 | 0.88 | TNF (0.42) | TNFMAPK10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483567 | 0.87 | TNF (0.35) | TNFPIK3CDPIK3CBPIK3CGMAPT | |
| SCHEMBL16483658 | 0.87 | TNF (0.39) | TNFMAPTNTSR1CYP17A1CYP1A2 | |
| SCHEMBL16483859 | 0.86 | TNF (0.37) | TNFMAPK10PIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |