SCHEMBL16484001

SCHEMBL16484001

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(-c4cccc(N(c5ccccn5)c5ccnc6ccccc56)c4)c4cccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ERN1 O75460 3/20 0.34
▸ ACVR1 Q04771 6/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TGFBR1 P36897 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ CHKA P35790 1/20 0.31
▸ MCL1 Q07820 1/20 0.31
▸ PIK3CA P42336 1/20 0.31
▸ GRM4 Q14833 1/20 0.30
▸ AURKA O14965 1/20 0.30
▸ TTK P33981 1/20 0.30
▸ AURKB Q96GD4 1/20 0.30
▸ INCENP Q9NQS7 1/20 0.30
▸ MMP1 P03956 1/20 0.30
▸ MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485069 0.92 ACVR1 (0.34) ERN1ACVR1MEN1LMNAHPGD
SCHEMBL16485323 0.91 CA12 (0.34) ERN1ACVR1MEN1LMNAHPGD
SCHEMBL16485092 0.90 MEN1 (0.33) ERN1MEN1LMNAHPGDKMT2A
SCHEMBL16483951 0.89 MEN1 (0.34) MEN1LMNAHPGDKMT2AMCL1
SCHEMBL16485088 0.89 ACVR1 (0.38) ERN1ACVR1MEN1LMNAHPGD
SCHEMBL16485065 0.88 MEN1 (0.33) MEN1LMNAHPGDKMT2A
SCHEMBL16483962 0.88 PIK3CA (0.37) ACVR1MEN1LMNAHPGDKMT2A
SCHEMBL16484495 0.87 MEN1 (0.34) ERN1ACVR1MEN1LMNAHPGD
SCHEMBL16483977 0.86 TGFBR1 (0.35) ACVR1MEN1LMNAHPGDKMT2A
SCHEMBL16483957 0.86 MEN1 (0.31) MEN1LMNAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 ERN1 4062/4885ACVR1 3793/4885MEN1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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