SCHEMBL16484352

SCHEMBL16484352

c1ccc2oc(-n3c4ccccc4c4ccccc43)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 11/20 0.61
GABRD O14764 11/20 0.61
GABRA1 P14867 11/20 0.61
GABRB1 P18505 11/20 0.61
GABRG2 P18507 11/20 0.61
GABRB3 P28472 11/20 0.61
GABRA5 P31644 11/20 0.61
GABRA3 P34903 11/20 0.61
GABRA2 P47869 11/20 0.61
GABRB2 P47870 11/20 0.61
GABRA4 P48169 11/20 0.61
GABRE P78334 11/20 0.61
GABRA6 Q16445 11/20 0.61
GABRG1 Q8N1C3 11/20 0.61
GABRG3 Q99928 11/20 0.61
GABRQ Q9UN88 11/20 0.61
CHRNA7 P36544 1/20 0.48
HTR3A P46098 1/20 0.48
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17989308 0.89 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16303056 0.89 GABRP (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17228182 0.87 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL21710986 0.87 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17246114 0.86 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17245406 0.86 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17245925 0.86 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17989304 0.85 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17989301 0.85 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL25449507 0.85 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 GABRP 4858/4885GABRD 4666/4885GABRA1 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.